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Tocris Bioscience™ PF 04449613, >98% Product Code.: 30000777
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Tocris Bioscience™ PF 04449613, >98%
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Product Code. 30000777
10 mg, 10mg
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Quantity:
10 mg
Unit Size:
10mg
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Product Code. 30000777

Brand: Tocris Bioscience™ 5915/10

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This item is not returnable. View return policy

Description

Potent PDE9 inhibitor; brain penetrant

PF 04449613 is a potent PDE9 inhibitor (IC50 = 22 nM). Also exhibits a high affinity for cGMP (Km ∼170 nM). PF 04449613 reduces body fat in mice with diet-induced obesity, stimulating mitochondrial activity in brown and white fat, and improving cardiometabolic syndrome symptoms. Brain penetrant.
Greener Choice Claims
  • Environmental benefits include:
    • Ozone-Safe or Safe for the Ozone Layer
TRUSTED_SUSTAINABILITY

Specifications

CAS 1236858-52-8
Quantity 10 mg
Solubility Soluble to 100mM in DMSO and to 10mM in 1eq. HCl with gentle warming
Molecular Formula C21H25N5O3
Formula Weight 395.45
Purity >98%
Molecular Weight (g/mol) 395.463
Chemical Name or Material 1,5-Dihydro-6-[(1R)-1-(3-phenoxy-1-azetidinyl)ethyl]-1-(tetrahydro-2H-pyran-4-yl)-4H-pyrazolo[3,4-d]
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