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Tocris Bioscience™ PF 3644022
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Product Code. 18085092
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Kvantitet:
10 mg
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18085092 10 mg
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Product Code. 18085092 Supplier Tocris Bioscience™ Supplier No. 4279/10

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Description

Potent MK2 inhibitor

Potent, ATP-competitive inhibitor of mitogen-activated protein kinase (MAPK)-activated protein kinase-2 (MK2) (IC50 = 5.2 nM; Ki = 3 nM). Inhibits tumor necrosis factor α (TNFα) production in U937 monocytic cells and peripheral blood mononuclear cells (PBMCs) (IC50 = 160 nM); exhibits oral efficacy in acute and chronic inflammatory models.
TRUSTED_SUSTAINABILITY

Specifications

Kemiskt namn eller material PF 3644022
CAS 1276121-88-0
Kvantitet 10 mg
Molekylformel C21H18N4OS
Formel vikt 374.46
Renhet >98%
Molekylvikt (g/mol) 374.462
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