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PFK-158, MedChemExpress
Beskrivning
PFK-158 is a potent and selective PFKFB3 inhibitor with an IC50 value 137 nM. PFK-158 reduces glucose uptake, ATP production, lactate release, and induces apoptosis and autophagy in cancer cells. PFK-158 has broad anti-tumor activity. PFK-158 can also enhance Colistin's resistance to bacteria.
Specifikationer
Specifikationer
| Kemiskt namn eller material | PFK-158 |
| Fysisk form | Solid |
| CAS | 1462249-75-7 |
| Färg | Light Yellow |
| Kvantitet | 100 mg |
| Anteckningar om renhetsgrad | Research |
| Molekylformel | C18H11F3N2O |
| För användning med (applikation) | Cancer-programmed cell death |
| Löslighetsinformation | DMSO : ≥ 30 mg/mL (91.38 mM) |
| LEDER | O=C(C1=CC=NC=C1)/C=C/C2=NC3=CC(C(F)(F)F)=CC=C3C=C2 |
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Research purposes only
Product Title
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