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Invitrogen™ PGRMC2 Polyclonal Antibody
Beskrivning
This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:1,000.
PGRMC2 (progesterone receptor membrane component 2), also known as DG6 (steroid receptor protein DG6) or PMBP (progesterone membrane-binding protein), is a single pass membrane protein belonging to the cytochrome b5 family (MAPR (membrane associated progesterone receptor) subfamily). Expressed in sperm, PGRMC2 is believed to function as a steroid receptor and may participate in the progesterone-dependent sperm acrosome reaction. PGRMC2 shares approximately 50% overall sequence identity with its close relative PGRMC1. The loss of the gene encoding PGRMC2 is associated with metastasis in uterine endocervical adenocarcinomas, implicating a potential role of PGRMC2 in the suppression of metastasis of endocervical adenocarcinomas.
Specifikationer
Specifikationer
| Antigen | PGRMC2 |
| Användningsområden | Flow Cytometry, Immunocytochemistry |
| Klassificering | Polyclonal |
| Koncentration | 0.5 mg/mL |
| Konjugera | Unconjugated |
| Formulering | TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3 |
| Gen | Pgrmc2 |
| Genaccessionsnr. | O15173 |
| Gene Alias | 4631434O19Rik; 5730409G06Rik; DG6; Membrane-associated progesterone receptor component 2; Pgrmc2; PMBP; progesterone membrane binding protein; Progesterone membrane-binding protein; progesterone receptor membrane component 2; steroid receptor protein DG6 |
| Gensymboler | Pgrmc2 |
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Produkttitel
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