missing translation for 'onlineSavingsMsg'
Läs mer
Läs mer
Invitrogen™ Phospho-DNA ligase IV (Thr650) Polyclonal Antibody

Beskrivning
Phospho-DNA ligase IV (Thr650) Polyclonal Antibody detects endogenous levels of DNA ligase IV only when phosphorylated at Thr650.
The protein encoded by this gene is a DNA ligase that joins single-strand breaks in a double-stranded polydeoxynucleotide in an ATP-dependent reaction. This protein is essential for V(D)J recombination and DNA double-strand break (DSB) repair through nonhomologous end joining (NHEJ). This protein forms a complex with the X-ray repair cross complementing protein 4 (XRCC4), and further interacts with the DNA-dependent protein kinase (DNA-PK). Both XRCC4 and DNA-PK are known to be required for NHEJ. The crystal structure of the complex formed by this protein and XRCC4 has been resolved. Defects in this gene are the cause of LIG4 syndrome. Alternatively spliced transcript variants encoding the same protein have been observed.
Specifikationer
Specifikationer
| Antigen | Phospho-DNA ligase IV (Thr650) |
| Användningsområden | Western Blot |
| Klassificering | Polyclonal |
| Koncentration | 1 mg/mL |
| Konjugera | Unconjugated |
| Formulering | PBS with 50% glycerol and 0.02% sodium azide; pH 7.4 |
| Gen | LIG4 |
| Genaccessionsnr. | P49917 |
| Gene Alias | 5830471N16Rik; DNA joinase; DNA ligase (ATP) 4; DNA ligase 4; DNA ligase IV; DNA repair enzyme; Lig4; LIG4S; ligase IV, DNA, ATP-dependent; polydeoxyribonucleotide synthase [ATP] 4; polynucleotide ligase; sealase; tiny |
| Gensymboler | LIG4 |
| Visa mer |
Produkttitel
Genom att klicka på Skicka bekräftar du att du kan bli kontaktad av Fisher Scientific angående feedbacken du har lämnat i detta formulär. Vi kommer inte att dela din information för andra ändamål. All kontaktinformation som tillhandahålls ska också underhållas i enlighet med vår Sekretesspolicy.
Hittar du en möjlighet till förbättring?