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Invitrogen™ Phospho-FADD (Ser194) Monoclonal Antibody (709736)
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Produktkod. 30533610
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Kvantitet:
100 μg
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Produktkod. Kvantitet
30533610 100 μg
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Produktkod. 30533610 Leverantör Invitrogen™ Leverantörsnummer MA561759

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Beskrivning

Mouse Monoclonal Antibody

Reconstitute with sterile PBS to a final concentration of 0.5 mg/mL.

The protein encoded by this gene is an adaptor molecule that interacts with various cell surface receptors and mediates cell apoptotic signals. Through its C-terminal death domain, this protein can be recruited by TNFRSF6/Fas-receptor, tumor necrosis factor receptor, TNFRSF25, and TNFSF10/TRAIL-receptor, and thus it participates in the death signaling initiated by these receptors. Interaction of this protein with the receptors unmasks the N-terminal effector domain of this protein, which allows it to recruit caspase-8, and thereby activate the cysteine protease cascade. Knockout studies in mice also suggest the importance of this protein in early T cell development.
TRUSTED_SUSTAINABILITY

Specifikationer

Antigen Phospho-FADD (Ser194)
Användningsområden Western Blot, Immunocytochemistry
Klassificering Monoclonal
Klona 709736
Koncentration 0.5 mg/mL
Konjugera Unconjugated
Formulering PBS with trehalose and no preservative
Gen FADD
Genaccessionsnr. Q13158
Gene Alias Fadd; Fas (TNFRSF6)-associated via death domain; Fas associated via death domain; FAS-associated death domain protein; FAS-associating death domain-containing protein; Fas-associating protein with death domain; GIG3; Growth-inhibiting gene 3 protein; mediator of receptor induced toxicity; mediator of receptor-induced toxicity; MGC8528; MORT1; Mort1/FADD; protein FADD
Gensymboler FADD
Värd art Mouse
Immunogen Phosphopeptide containing the human FADD S194 site.
Reningsmetod Protein A/G
Kvantitet 100 μg
Regulatorisk status RUO
Primär eller sekundär Primary
Gen-ID (Entrez) 8772
Målarter Human
Innehåll och lagring Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Produkttyp Antibody
Form Lyophilized
Isotyp IgG2a
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Produkttitel
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