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Invitrogen™ Phospho-FGFR4 (Tyr642) Polyclonal Antibody
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Produktkod. 15504521
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Kvantitet:
100 μL
Förpackningsstorlek:
100µL
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15504521 100 μL 100µL
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Produktkod. 15504521 Leverantör Invitrogen™ Leverantörsnummer PA537576

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Beskrivning

Rabbit Polyclonal Antibody

A suggested positive control for Western blot is JK cells.

FGFR4 is a member of the FGFR family of receptor tyrosine kinases. This family is known to regulate a host of cellular functions including angiogenesis, mitogenesis, osteogenesis, myogenesis, carcinogenesis, cellular differentiation, and tissue repair after injury. The FGFR family has also been implicated in a number of diseases including cancer, rheumatoid arthritis, and diabetic retinopathy. FGFR4 is required for normal down-regulation of the expression of CYP7A1, the rate-limiting enzyme in bile acid synthesis, in response to FGF19. FGFR4 plays a role in postnatal lung development and may be involved in the development of skeletal muscle cell lineages.
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Specifikationer

Antigen Phospho-FGFR4 (Tyr642)
Användningsområden Western Blot
Klassificering Polyclonal
Koncentration 1 mg/mL
Konjugera Unconjugated
Formulering PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gen Fgfr4
Genaccessionsnr. P22455, Q03142, Q498D6
Gene Alias CD334; CTLA-2-beta protein; FGF Receptor; FGF Receptor 4; FGFR; Fgfr4; FGFR-4; Fibroblast growth factor receptor 4; fibroblast growth factor receptor 4 16 minus form; hydroxyaryl-protein kinase; JTK2; MGC20292; Mpk-11; protein-tyrosine kinase; protein-tyrosine kinase receptor MPK-11; TKF; tyrosine kinase related to fibroblast growth factor receptor; tyrosylprotein kinase
Gensymboler Fgfr4
Värd art Rabbit
Immunogen Peptide sequence around phosphorylation site of tyrosine 642(I-D-Y(p)-Y-K) derived from Human FGFR4.
Reningsmetod Antigen affinity chromatography
Kvantitet 100 μL
Regulatorisk status RUO
Primär eller sekundär Primary
Gen-ID (Entrez) 14186, 2264, 25114
Målarter Human, Mouse, Rat
Innehåll och lagring -20°C
Produkttyp Antibody
Form Liquid
Isotyp IgG
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