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Invitrogen™ Phospho-GAB2 (Ser159) Polyclonal Antibody

Produktkod. 15514531
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Kvantitet:
100 μL
Förpackningsstorlek:
100µL
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15514531 100 μL 100µL
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Produktkod. 15514531 Leverantör Invitrogen™ Leverantörsnummer PA537587

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Beskrivning

Rabbit Polyclonal Antibody

The antibody detects endogenous levels of GAB2 only when phosphorylated at serine 159. A suggested positive control for Western blot is HT29 cells.

This gene is a member of the GRB2-associated binding protein (GAB) gene family. These proteins contain pleckstrin homology (PH) domain, and bind SHP2 tyrosine phosphatase and GRB2 adapter protein. They act as adapters for transmitting various signals in response to stimuli through cytokine and growth factor receptors, and T- and B-cell antigen receptors. The protein encoded by this gene is the principal activator of phosphatidylinositol-3 kinase in response to activation of the high affinity IgE receptor. Two alternatively spliced transcripts encoding different isoforms have been described for this gene.
TRUSTED_SUSTAINABILITY

Specifikationer

Antigen Phospho-GAB2 (Ser159)
Användningsområden Western Blot
Klassificering Polyclonal
Koncentration 1 mg/mL
Konjugera Unconjugated
Formulering PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gen GAB2
Genaccessionsnr. Q9UQC2
Gene Alias AI463667; D130058I17Rik; GAB2; Grb2 associated binder 2; GRB2 associated binding protein 2; GRB2-associated binder 2; GRB2-associated binding protein 2; GRB2-associated-binding protein 2; GRB3-3; Growth factor receptor bound protein 2-associated protein 2; KIAA0571; p97; PH domain-containing adaptor molecule p97; pp100
Gensymboler GAB2
Värd art Rabbit
Immunogen Peptide sequence around phosphorylation site of Serine 159(K-S-S(p)-A-P) derived from Human GAB2.
Reningsmetod Antigen affinity chromatography
Kvantitet 100 μL
Regulatorisk status RUO
Primär eller sekundär Primary
Gen-ID (Entrez) 9846
Målarter Human
Innehåll och lagring -20°C
Produkttyp Antibody
Form Liquid
Isotyp IgG
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