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Phospho-Histone H3 (S28) Rat anti-Human, Mouse, eFluor 660, Clone: HTA28, eBioscience™

Rat Monoclonal Antibody

Brand:  Affymetrix eBioscience 50-9124-41

Additional Details : Weight : 0.23750kg

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Product Code. 15500087

  • 991.00 SEK / 25 tests


Estimated Shipment date
from Supplier 26-09-2017
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Disclaimers:

For Research Use Only.


Description

Description

The HTA28 monoclonal antibody recognizes phosphorylated serine 28 of human, mouse, rat, bovine, and hamster histone H3. This 15kDa protein is a component of eukaryotic chromatin that is involved in forming the nucleosome structure. Histone H3 can be phosphorylated at serine 10 and serine 28. Studies have demonstrated that phosphorylation at serine 28 is mediated by MSK1 following activation by the MAP kinase signaling pathway in response to tumor promoters (e.g., UV and EGF) and oncoproteins (e.g., c-Myc, c-Jun, and c-Fos). Histone H3 serine 28 phosphorylation has been linked to chromosome condensation during mitosis, cell transformation, and regulation of RNA polymerase III transcription machinery.
Specifications

Specifications

Phospho-Histone H3 (S28)
HTA28
eFluor 660
Conjugated
IgG2a
RUO
Primary
Murine
Flow Cytometry (Intracellular Staining)
5μL (0.25μg)/test
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Rat
25 Tests
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal