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Invitrogen™ Phospho-NFkB p65 (Ser536) Monoclonal Antibody (T.849.2)

Produktkod. 11509481
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Kvantitet:
100 μL
Förpackningsstorlek:
100µL
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Produktkod. Kvantitet Förpackningsstorlek
11509481 100 μL 100µL
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Produktkod. 11509481 Leverantör Invitrogen™ Leverantörsnummer MA515160
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Beskrivning

Rabbit Monoclonal Antibody

It is not recommended to aliquot this antibody. This antibody is not cross-reactive with the p50 subunit or other related proteins.

Nuclear factor kB p65 (NF-kB p65) is encoded by the RELA gene and is present on chromosome 11 in humans. NF-kB P65 is also known as RelA (v-rel avian reticuloendotheliosis viral oncogene homolog A) and belongs to the Rel family of proteins. It is one of the two subunits of NF-kB (Nuclear factor kappa-light-chain-enhancer of activated B cells) that heterodimerizes with the other subunits p50 or p52. However, binding of TNF alpha to its cognate receptor phosphorylates IKK which in turn phosphorylates I kB allowing proteasomal degradation of I kB. It specifically plays a key role in transcription of immunoglobulin k (kappa) gene in mature B-lymphoid cells.
TRUSTED_SUSTAINABILITY

Specifikationer

Antigen Phospho-NFkB p65 (Ser536)
Användningsområden Flow Cytometry, Immunoprecipitation, Western Blot, Immunocytochemistry
Klassificering Monoclonal
Klona T.849.2
Koncentration 57 μg/mL
Konjugera Unconjugated
Formulering 0.01M HEPES with 50% glycerol, 0.15M NaCl, 100 μg/mL BSA and <0.02% sodium azide, pH 7.5
Gen RELA
Genaccessionsnr. Q04206, Q04207
Gene Alias avian reticuloendotheliosis viral (v-rel) oncogene homolog A; EBP-1; I79_021812; MGC131774; NF KB; NFkappaB p65; nf-kappa-b p65; NF-kappa-B p65delta3; NF-kappa-B transcription factor p65; NF-kappaB transcription factor p65 subunit; NFkB; NF-kB p65; NF-kB p65 subunit; nfkb rela; NFKB1; nfkb3; NFkB-p50; nuclear factor; nuclear factor kappa b; nuclear factor kappa B subunit p65; nuclear factor NF-kappa-B p65 subunit; Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3; p65; p65 NF kappaB; p65 NF-kappa B; p65 NFkB; P65 transcription factor; putative transcription factor p65 homolog; REL A; rel1; rela; RELA proto-oncogene, NF-kB subunit; rela.L; rela-a; Transcription factor p65; v-rel avian reticuloendotheliosis viral oncogene homolog A; v-rel avian reticuloendotheliosis viral oncogene homolog A L homeolog; v-rel reticuloendotheliosis viral oncogene homolog A; v-rel reticuloendotheliosis viral oncogene homolog A (avian); v-rel reticuloendotheliosis viral oncogene homolog A, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3, p65; XELAEV_18022301mg; Xrel1; xrela
Gensymboler RELA
Värd art Rabbit
Immunogen Synthetic phosphopeptide corresponding to residues surrounding pSer536 of human NFkB p65.
Reningsmetod Affinity chromatography
Kvantitet 100 μL
Regulatorisk status RUO
Primär eller sekundär Primary
Gen-ID (Entrez) 100135665, 100763542, 19697, 309165, 5970
Målarter Human, Mouse, Rat, Monkey, Hamster, Pig
Innehåll och lagring -20°C
Produkttyp Antibody
Form Liquid
Isotyp IgG
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