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Phospho-Rb (Ser612) Polyclonal Antibody, Invitrogen™
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Produktkod. 10027869
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Kvantitet:
400 μL
Förpackningsstorlek:
100µg
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10027869 400 μL 100µg
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Produktkod. 10027869 Leverantör Invitrogen Leverantörsnummer PA512680

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Rabbit Polyclonal Antibody

Rb is a tumor suppressor nuclear phosphoprotein capable of binding to DNA. It is phosphorylated on serine and threonine, but not on tyrosine residues. It forms a complex with SV40 large T antigen, adenovirus E1A, and human papilloma virus-16 E. Rb protein may act by regulating transcription and loss of its function leads to uncontrolled cell growth. Aberrations in the RB gene have been implicated in cancers of breast, colon, prostate, kidney, nasopharynx, and leukemia.
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Specifikationer

Antigen Phospho-Rb (Ser612)
Användningsområden Immunohistochemistry (Paraffin), Western Blot
Klassificering Polyclonal
Koncentration 0.5 mg/mL
Konjugera Unconjugated
Formulering PBS with 0.09% sodium azide
Gen RB1
Genaccessionsnr. P06400
Gene Alias Cleaved Rb; delta RB-p70; DRb-p70; exon 17 tumor GOS561 substitution mutation causes premature stop; GOS563 exon 17 substitution mutation causes premature stop; OSRC; p104; p104 chicken Rb; P105RB; p105-Rb; Phospho-Retinoblastoma; pp105; pp110; PPP1R130; pRb; prepro-retinoblastoma-associated protein; protein phosphatase 1, regulatory subunit 130; rb; RB transcriptional corepressor 1; RB1; Rb-1; Rb-p70; Retin; Retinoblastoma; retinoblastoma 1; retinoblastoma 1 (including osteosarcoma); retinoblastoma 1 protein; retinoblastoma gene; retinoblastoma isoform A; retinoblastoma protein; retinoblastoma suspectibility protein; retinoblastoma tumor suppressor; retinoblastoma-associated protein
Gensymboler RB1
Värd art Rabbit
Immunogen KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S612 of human RB
Reningsmetod Antigen affinity chromatography, Protein A
Kvantitet 400 μL
Regulatorisk status RUO
Primär eller sekundär Primary
Gen-ID (Entrez) 5925
Målarter Human
Innehåll och lagring -20° C, Avoid Freeze/Thaw Cycles
Produkttyp Antibody
Form Liquid
Isotyp IgG
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Produkttitel
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