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Phospho-S6 (Ser235, Ser236) Mouse anti-Human, Mouse, Clone: cupk43k, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 14-9007-80

Additional Details : Weight : 0.09500kg

Product Code. 15507566

  • 1216.00 SEK / 25µg


Estimated Shipment date
from Supplier 25-04-2019
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Description

Description

It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. Purity: Greater than 90%, as determined by SDS-PAGE. Aggregation: Less than 10%, as determined by HPLC. Filtration: 0.2 μm post-manufacturing filtered. Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a cytoplasmic ribosomal protein that is a component of the 40S subunit. The protein belongs to the S6E family of ribosomal proteins. It is the major substrate of protein kinases in the ribosome, with subsets of five C-terminal serine residues phosphorylated by different protein kinases. Phosphorylation is induced by a wide range of stimuli, including growth factors, tumor-promoting agents, and mitogens. Dephosphorylation occurs at growth arrest. The protein may contribute to the control of cell growth and proliferation through the selective translation of particular classes of mRNA. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.
Specifications

Specifications

Phospho-S6 (Ser235, Ser236)
Monoclonal
0.5 mg/mL
PBS with 0.09% sodium azide; pH 7.2
P62753, P62754
40S ribosomal protein S6; Phosphoprotein NP33
Mouse
Affinity chromatography
RUO
Antibody
Monoclonal
Human, Mouse
Flow Cytometry, Western Blot
cupk43k
Unconjugated
RPS6
Liquid
RPS6
IgG1, kappa
25 μg
4° C
Primary
20104, 6194
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