Phospho-S6 (Ser235, Ser236) Mouse anti-Human, Mouse, Clone: cupk43k, eBioscience™
Mouse Monoclonal Antibody
Brand: Affymetrix eBioscience 14-9007-80
Additional Details : Weight : 0.09500kg
DescriptionIt is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. Purity: Greater than 90%, as determined by SDS-PAGE. Aggregation: Less than 10%, as determined by HPLC. Filtration: 0.2 μm post-manufacturing filtered. Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a cytoplasmic ribosomal protein that is a component of the 40S subunit. The protein belongs to the S6E family of ribosomal proteins. It is the major substrate of protein kinases in the ribosome, with subsets of five C-terminal serine residues phosphorylated by different protein kinases. Phosphorylation is induced by a wide range of stimuli, including growth factors, tumor-promoting agents, and mitogens. Dephosphorylation occurs at growth arrest. The protein may contribute to the control of cell growth and proliferation through the selective translation of particular classes of mRNA. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.
|Phospho-S6 (Ser235, Ser236)|
|PBS with 0.09% sodium azide; pH 7.2|
|40S ribosomal protein S6; Phosphoprotein NP33|
|Flow Cytometry, Western Blot|
For Research Use Only.