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Invitrogen™ Phospho-SMAD2/SMAD3 (Thr8) Polyclonal Antibody
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Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA536028

Produktkod. 15577481

  • 5040.00 SEK / 100µL

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Beskrivning

Beskrivning

This antibody detects endogenous protein at a molecular weight of 55 and 60 kDa. Purity is >95% by SDS-PAGE.

Smad proteins, the mammalian homologs of the Drosophila mothers against decapentaplegic (Mad), have been implicated as downstream effectors of TGFβ/BMP signaling. Smad1 (also designated Madr1 or JV4-1) and Smad5 are effectors of BMP-2 and BMP-4 function, while Smad2 (also designated Madr2 or JV18-1) and Smad3 are involved in TGFβ and Activin-mediated growth modulation. Smad4 (also designated DPC4) has been shown to mediate all of the above activities through interaction with various Smad family members. Smad6 and Smad7 regulate the response to Activin/TGFβ signaling by interfering with TGFβ-mediated phosphorylation of other Smad proteins.
TRUSTED_SUSTAINABILITY
Specifikationer

Specifikationer

Phospho-SMAD2/SMAD3 (Thr8)
Polyclonal
Unconjugated
SMAD2
7120426M23Rik; AU022421; hMAD-2; hMAD-3; hSMAD2; hSMAD3; HSPC193; HsT17436; JV15-2; JV18; JV18-1; LDS1C; LDS3; MAD (mothers against decapentaplegic, Drosophila) homolog 3; MAD homolog 2; MAD homolog 3; mad homolog JV15-2; mad protein homolog; MAD, mothers against decapentaplegic homolog 3; mad3; MADH2; MADH3; MADR2; mad-related protein 2; mMad2; mMad3; mother against DPP homolog 2; mothers against decapentaplegic homolog 2; Mothers against decapentaplegic homolog 3; mothers against DPP homolog 2; mothers against DPP homolog 3; pSMAD2; Sma- and Mad-related protein 2; SMA- and MAD-related protein 3; SMAD; Smad 2; Smad 3; SMAD family member 2; SMAD family member 3; SMAD, mothers against DPP homolog 2; SMAD, mothers against DPP homolog 3; Smad2; Smad-2; Smad3
Rabbit
Antigen Affinity Chromatography
RUO
17126, 17127, 25631, 29357, 4087, 4088
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
Immunoprecipitation, Western Blot, Immunocytochemistry
1 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
O70436, P84022, P84025, Q15796, Q62432, Q8BUN5
SMAD2, SMAD3
Synthetic phosphopeptide derived from human Smad2/3 around the phosphorylation site of Threonine 8.
100 μL
Primary
Human, Mouse, Rat
Antibody
IgG
Produktförslag

Produktförslag

Filmer
SDS
Dokument

Dokument

Certifikat
Kampanjer

Kampanjer

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