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Phospho-STAT1 (Tyr701) Monoclonal Antibody (KIKSI0803), PE-eFluor™ 610, eBioscience™, Invitrogen™
Mouse Monoclonal Antibody
2640.00 SEK - 6410.00 SEK
Specifications
| Antigen | Phospho-STAT1 (Tyr701) |
|---|---|
| Clone | KIKSI0803 |
| Concentration | 5 μL/Test |
| Applications | Flow Cytometry |
| Classification | Monoclonal |
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|
16606474
|
Affymetrix eBioscience
61-9008-42 |
100 Tests |
6410.00 SEK
Pack of 100 |
Estimated Shipment: 03-05-2024 Log in to see stock. |
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|
16696464
|
Affymetrix eBioscience
61-9008-41 |
25 Tests |
This item is currently unavailable or has been discontinued. View the product page for possible alternatives. |
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Description
This KIKSI0803 MAb recognizes signal transducer and activator of transcription 1 (STAT1) when phosphorylated on tyrosine 701. STAT proteins are activated by ligand binding to receptors, such as cytokine receptors, that associate with Janus kinase (JAK) family members. Following their phosphorylation by JAKs, STAT proteins translocate to the nucleus where they bind to DNA and regulate transcription of specific genes in a cell type- and cytokine-specific manner. Phosphorylation of STAT1 on tyrosine 701 by JAK1 and JAK2 is essential for STAT1 dimer formation, nuclear translocation, and DNA binding activity. In response to IFN gamma stimulation, STAT1 homodimerizes or forms heterodimers with STAT3 that can bind to GAS (IFN gamma-activated sequence) promoter elements. In response to either IFN alpha or IFN beta stimulation, STAT1 forms a heterodimer with STAT2 that can bind ISRE (IFN-stimulated response element) promoter elements. Specificity of this KIKSI0803 clone was determined by ELISA, flow cytometry, and western blotting.
Phospho-STAT1 (Tyr701) Monoclonal antibody specifically detects Phospho-STAT1 (Tyr701) in Human samples. It is validated for Flow Cytometry.Specifications
| Phospho-STAT1 (Tyr701) | |
| 5 μL/Test | |
| Monoclonal | |
| Liquid | |
| RUO | |
| PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2 | |
| 6772 | |
| Primary | |
| 4° C, store in dark, DO NOT FREEZE! | |
| STAT1 |
| KIKSI0803 | |
| Flow Cytometry | |
| PE-eFluor 610 | |
| Mouse | |
| Human | |
| P42224 | |
| IgG1 κ | |
| Affinity chromatography | |
| Antibody |