missing translation for 'onlineSavingsMsg'
Learn More
Thermo Scientific™ Pierce™ EDC, No-Weigh™ Format Product Code.: 11861335
compliance-icons

Thermo Scientific™ Pierce™ EDC, No-Weigh™ Format

Product Code. 11861335 Shop All Thermo Scientific Products
25 g, 25g
Click to view available options
Quantity:
10 mg
10 x 1 mg
5 g
25 g
Unit Size:
10mg
25g
5g
Pack of 10
This item is not returnable. View return policy

Product Code. 11861335

Brand: Thermo Scientific™ 22981

Please to purchase this item. Need a web account? Register with us today!

This item is not returnable. View return policy

Immobilize or conjugate proteins using 1-Ethyl-3-(3-dimethylaminopropyl) carbodiimide (CAS 25952-53-8), a water-soluble, carboxyl-to-amine crosslinker.

Thermo Scientific™ Pierce EDC is a water-soluble carbodiimide crosslinker that activates carboxyl groups for spontaneous reaction with primary amines, enabling peptide immobilization and hapten-carrier protein conjugation.

EDC is the abbreviation for 1-Ethyl-3-(3-dimethylaminopropyl)carbodiimide hydrochloride, a crosslinker that has been used in diverse applications such as forming amide bonds in peptide synthesis, attaching haptens to carrier proteins to form immunogens, labeling nucleic acids through 5Æphosphate groups and creating amine-reactive NHS-esters of biomolecules. EDC reacts with a carboxyl to form an amine-reactive O-acylisourea intermediate. If this intermediate does not encounter an amine, it will hydrolyze and regenerate the carboxyl group. In the presence of N-hydroxysulfosuccinimide (Sulfo-NHS, Part No. 24510), EDC can be used to convert carboxyl groups to amine-reactive Sulfo-NHS esters.

Highlights:

  • Zero-length crosslinker
  • Numerous chemical conjugates can be synthesized via available –COOH and –NH2 groups
  • Amide bond formed provides a neutral linkage, which is ideal for preparing peptides and antigens
  • Adding Sulfo-NHS (Part No. 24510) enhances the coupling reaction at physiological pH conditions
  • Reactive groups: carbodiimide
  • Reactive toward: carboxyl and amino groups
TRUSTED_SUSTAINABILITY

Specifications

Chemical Reactivity Amine-Carboxyl
Cleavable No
Description EDC
Molecular Weight (g/mol) 191.7
PEGylated No
Spacer Arm Length 0.0 Å
Content And Storage Upon receipt store desiccated at -20°C.
Cell Permeability No
Shipping Condition Wet Ice
Product Line Pierce™
Labeling Method Chemical Labeling
Crosslinker Type Heterobifunctional
Reactive Moiety Carbodiimide
Spacer Short (<10 Å)
Form Powder
Quantity 25 g
Solubility Water
Format Standard, Single-use, Premium-grade
Water Soluble Yes
Product Type Crosslinker
Show More Show Less

Certificates

A lot number is required to show results for certificates. To find your lot number on previous orders use our order status area.

5 results found
Lot Number Certificate Type Date Product Code
Lot NumberZJ385304 Certificate TypeCertificate of Analysis Date16/12/2024 Product Code22981
Lot NumberZD384625 Certificate TypeCertificate of Analysis Date07/05/2024 Product Code22981
Lot NumberYL382353 Certificate TypeCertificate of Analysis Date25/01/2024 Product Code22981
Lot NumberYI380447 Certificate TypeCertificate of Analysis Date22/09/2023 Product Code22981
Lot NumberYG376457 Certificate TypeCertificate of Analysis Date11/08/2023 Product Code22981
compliance-icons
Product Identifier
  • EDC (1-ethyl-3-(3-dimethylaminopropyl)carbodiimide hydrochloride)
Signal Word
  • Warning
Hazard Category
  • Serious eye damage/eye irritation Category 2
  • Skin corrosion/irritation Category 2
  • Specific target organ toxicity Category 3
Hazard Statement
  • H315-Causes skin irritation.
  • H319-Causes serious eye irritation.
  • H335-May cause respiratory irritation.
Precautionary Statement
  • P261-Avoid breathing dust/fume/gas/mist/vapours/spray.
  • P264-Wash hands thoroughly after handling.
  • P271-Use only outdoors or in a well-ventilated area.
  • P280-Wear protective gloves/protective clothing/eye protection/face protection.
  • P302+P352-IF ON SKIN: Wash with plenty of water/soap.
  • P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.
  • P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P312-Call a POISON CENTER/doctor/if you feel unwell.
  • P332+P313-If skin irritation occurs: Get medical advice/attention.
  • P337+P313-If eye irritation persists: Get medical advice/attention.
  • P362+P364-Take off contaminated clothing and wash it before reuse.
  • P501b-Dispose of contents/container in accordance with local/regional/national/international regulations.
Supplemental information
  • MIXTURE LIST-Contains : N-(ethylcarbonimidoyl)-N,N-dimethyl-1,3-propanediamine monohydrochloride

For Research Use Only. Not for use in diagnostic procedures.

Product Content Correction

Your input is important to us. Please complete this form to provide feedback related to the content on this product.

Product Title
Thermo Scientific™ Pierce™ EDC, No-Weigh™ Format >

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Thank You! Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.