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Invitrogen™ Human PIK3C2G (PI3K-C2 gamma), GST Tag Recombinant Protein

Produktkod. 15970313
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Kvantitet:
1 mg
100 μg
20 μg
Förpackningsstorlek:
100µg
1mg
20µg
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Produktkod. 15970313

Brand: Invitrogen™ A31081

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Beskrivning

Recombinant Protein

For maximum recovery please spin prior to use. Unless noted below, aliquots of the 5 μg, 10 μg and 20 μg sizes of kinase are not recommended as materials can be used in original packaging until exhausted. For larger sizes, the number of freeze/thaws may be reduced by preparing aliquots, aliquots below 20 μL are not recommended. Please never store a kinase diluted. If properly stored at -80C, this product is guaranteed for 6 months from date of purchase. This PIK3C2G (PI3K-C2 gamma) recombinant human protein (468-1203) was expressed in insect cells. PIK3C2G (PI3K-C2 gamma) recombinant human protein is also available in our SelectScreen™ Kinase Profiling Service. Validated for use with the Adapta™ assay Available in multiple pack sizes for convenient use Also available in our SelectScreen Kinase Profiling Service Protein Form: Recombinant, Active, Catalytic The gene accession number for PIK3C2G (PI3K-C2 gamma) is AAI30278.1.

PIK3C2G lipid kinase belongs to the phosphoinositide 3-kinase (PI3K) family which play major roles in signaling pathways and are involved in cell proliferation, oncogenic transformation, cell survival, cell migration, and intracellular protein trafficking. PIK3C2G contains a lipid kinase catalytic domain as well as a C-terminal C2 domain, a characteristic of class II PI3-kinases that act as calcium-dependent phospholipid binding motifs which mediate translocation of proteins to membranes, and may also mediate protein-protein interactions. The N-terminal region of PIK3C2G and the C-terminal C2 domain are required for enzymatic activity. The PI 3-kinase C2gamma gene encodes a 1,050 amino acid polypeptide with 36% identity to human PI 3-kinase C2alpha. Research indicates that PI 3-kinase C2gamma can block the growth of human colon cancer cells.
TRUSTED_SUSTAINABILITY

Specifikationer

Tillträdesnummer O75747
Koncentration See Label
För användning med (applikation) Kinase Assay
Formulering 50mM tris HCl with 0.1mM PMSF, 0.25mM DTT, 25% glycerol, 0.1mM EDTA, 10mM glutathione, 150mM NaCl and no preservative; pH 7.5
Gen-ID (Entrez) 5288
Molekylvikt (g/mol) 110 kDa
Namn Human PIK3C2G (PI3K-C2 gamma), GST Tag
pH-intervall 7.5
Reningsmetod Purified
Kvantitet 20 μg
Förvaringskrav -80°C, Avoid Freeze/Thaw Cycles
Regulatorisk status RUO
Gene Alias C80387; phosphatidylinositol 3-kinase, C2 domain containing, gamma polypeptide; phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma; phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing gamma polypeptide; phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing subunit gamma; phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma; phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 gamma; phosphoinositide 3-Kinase-C2-gamma; phosphoinositide-3-kinase, class 2, gamma polypeptide; PI 3-kinase C2gamma; PI3KC2gamma; PI3K-C2gamma; PI3K-C2-gamma; Pik3c2g; PTDINS-3-kinase C2 gamma; ptdIns-3-kinase C2 subunit gamma
Vanligt namn PIK3C2G
Gensymbol PIK3C2G
KinaseFamily PI3 Kinase
Protein Längd 468-1203
Produkttyp Protein
Konjugera Unconjugated
Art Human
Rekombinant Recombinant
Protein Tag GST-tag
Sekvens 468-1203
Innehåll och lagring -80°C, Avoid Freeze/Thaw Cycles
Frakt skick Dry Ice
Uttryckssystem Insect cells
Proteinfamilj Kinases & Inhibitors
Proteinform Recombinant, Active, Catalytic
Form Liquid
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