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PIK3C2G Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Brand: Invitrogen PA515239
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Description
PIK3C2G lipid kinase belongs to the phosphoinositide 3-kinase (PI3K) family which play major roles in signaling pathways and are involved in cell proliferation, oncogenic transformation, cell survival, cell migration, and intracellular protein trafficking. PIK3C2G contains a lipid kinase catalytic domain as well as a C-terminal C2 domain, a characteristic of class II PI3-kinases that act as calcium-dependent phospholipid binding motifs which mediate translocation of proteins to membranes, and may also mediate protein-protein interactions. The N-terminal region of PIK3C2G and the C-terminal C2 domain are required for enzymatic activity. The PI 3-kinase C2gamma gene encodes a 1,050 amino acid polypeptide with 36% identity to human PI 3-kinase C2alpha. Research indicates that PI 3-kinase C2gamma can block the growth of human colon cancer cells.
Specifications
| PIK3C2G | |
| Polyclonal | |
| Unconjugated | |
| PIK3C2G | |
| C80387; phosphatidylinositol 3-kinase, C2 domain containing, gamma polypeptide; phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma; phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing gamma polypeptide; phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing subunit gamma; phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma; phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 gamma; phosphoinositide 3-Kinase-C2-gamma; phosphoinositide-3-kinase, class 2, gamma polypeptide; PI 3-kinase C2gamma; PI3KC2gamma; PI3K-C2gamma; PI3K-C2-gamma; Pik3c2g; PTDINS-3-kinase C2 gamma; ptdIns-3-kinase C2 subunit gamma | |
| Rabbit | |
| Ammonium sulfate precipitation, Size-exclusion - Dialysis | |
| RUO | |
| 5288 | |
| -20° C, Avoid Freeze/Thaw Cycles | |
| Liquid |
| Immunohistochemistry (Paraffin), Western Blot | |
| 1 mg/mL | |
| PBS with 0.09% sodium azide | |
| O75747 | |
| PIK3C2G | |
| KLH conjugated synthetic peptide between 93-123 amino acids from the N-terminal region of human PI3KC2G | |
| 400 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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