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Invitrogen™ PKA alpha Monoclonal Antibody
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Kvantitet:
100 μL
Förpackningsstorlek:
100µL
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Produktkod. Kvantitet unitSize
17256733 100 μL 100µL
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Produktkod. 17256733 Leverantör Invitrogen™ Leverantörsnummer MA537857

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Beskrivning

Mouse Monoclonal Antibody

Positive Samples: HeLa, PC-3, C6, Mouse testis, Mouse brain, Rat testis.

Protein kinase A (PKA, cAMP-dependent protein kinase) is a key element of a ubiquitous signaling pathway important in the cell cycle, cellular communication, memory formation and behavior. PKA is composed of two catalytic (PKAc; Protein Kinase A catalytic subunit) and two regulatory subunits (PKAr). Upon binding cAMP, the complex dissociates to PKAr dimer and two activated PKAc ser/thr protein kinase catalytic monomers. The released PKAc can translocate into the nucleus and exert a regulatory role in the activation of multiple nuclear hormone receptors. However, PKAc-mediated activation of tonicity-dependent gene expression is cAMP independent. Humans express three types of PKAc subunit - PKAc alpha is present in most human tissues, PKAc beta and gamma are tissue-specific, the later is found in testes.
TRUSTED_SUSTAINABILITY

Specifikationer

Antigen PKA alpha
Användningsområden ELISA, Western Blot, Immunocytochemistry
Klassificering Monoclonal
Koncentration 0.5 mg/mL
Konjugera Unconjugated
Formulering PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3
Gen PRKACA
Genaccessionsnr. P05132, P17252, P27791
Gene Alias alternatively spliced; C(s); Calpha; C-alpha-2; C-alpha-S; cAMP-dependent protein kinase catalytic subunit alpha; cAMP-dependent protein kinase catalytic subunit alpha, isoform 1; cAMP-dependent protein kinase catalytic subunit C alpha; cAMP-dependent protein kinase catalytic subunit Calpha1; Cs-PKA; MGC102831; MGC48865; PKA; PKA C-alpha; PKA catalytic subunit alpha; pkac; Pkaca; PKCA1; PKCD; PPNAD4; PRKACA; protein kinase; protein kinase A; protein kinase A alpha; protein kinase A catalytic subunit; protein kinase cAMP-activated catalytic subunit alpha; protein kinase, cAMP dependent, catalytic, alpha; protein kinase, cAMP-dependent, alpha catalytic subunit; protein kinase, cAMP-dependent, catalytic, alpha; sperm cAMP-dependent protein kinase catalytic subunit; sperm cAMP-dependent protein kinase catalytic subunit Cs
Gensymboler PRKACA
Värd art Mouse
Immunogen Recombinant protein of human PKA C-alpha (PRKACA).
Reningsmetod Affinity chromatography
Kvantitet 100 μL
Regulatorisk status RUO
Primär eller sekundär Primary
Gen-ID (Entrez) 18747, 25636, 5566
Målarter Human, Mouse, Rat
Innehåll och lagring -20°C, Avoid Freeze/Thaw Cycles
Produkttyp Antibody
Form Liquid
Isotyp IgG2b κ
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