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Invitrogen™ PKC zeta Polyclonal Antibody

Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA529337
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Beskrivning
Recommended positive controls: U87-MG, SK-N-SH, IMR32, SK-N-AS. Predicted reactivity: Mouse (99%), Rat (99%), Zebrafish (91%), Pig (99%), Rabbit (99%), Bovine (99%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
The PKC family of serine/threonine kinases, including PRKCZ (PKC zeta), is activated intracellularly by signal transduction pathways. In humans, at least 12 different PKC polypeptides have been identified. These isoforms differ in primary structure, tissue distribution, subcellular localization, mode of action in vitro, response to extracellular signals, and substrate specificity. PKC alpha, beta I, beta II and gamma form the conventional family; their activities are Ca2+- and phospholipid-dependent. PKC zeta plays a key regulatory role in a variety of cellular functions including cell growth and differentiation, gene expression, hormone secretion and membrane function.
Specifikationer
| PKC zeta | |
| Polyclonal | |
| Unconjugated | |
| PRKCZ | |
| 14 - 3 - 3 - zeta isoform; 14-3-3-zetaisoform; AI098070; aPKCzeta; atypical protein kinase C; C80388; kinase nPKC-zeta; KPCZ; nPKC-zeta; nPKC-zeta PRKCZ; PKC2; Pkcz; PKC-ZETA; Prkcz; protein kinase C zeta; protein kinase C zeta subspecies; protein kinase C zeta type; protein kinase C, zeta; r14-3-3; R74924; zetaPKC | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 5590 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Immunohistochemistry (Paraffin), Western Blot | |
| 0.5 mg/mL | |
| 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7 | |
| Q05513 | |
| PRKCZ | |
| Recombinant protein encompassing a sequence within the center region of human PKC zeta. The exact sequence is proprietary. | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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