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Invitrogen™ PLD2 Polyclonal Antibody
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Produktkod. 30535432
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Kvantitet:
100 μg
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Produktkod. Kvantitet
30535432 100 μg
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Produktkod. 30535432 Leverantör Invitrogen™ Leverantörsnummer PA5148466

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Goat Polyclonal Antibody

Reconstitute at 0.2 mg/mL in sterile PBS.

PLD2 is a peripheral membrane protein belonging to phospholipase D family with a PH domain, two PLD phosphodiesterase domains and a PX (phox homology) domain that plays a regulatory rather than catalytic role. PLD2 catalyzes the hydrolysis of phosphatidylcholine (PC) to produce phosphatidic acid and choline. PLD2 may function in regulated secretion, signal-induced cytoskeletal regulation and/or endocytosis, transcriptional regulation, and cell cycle control. It is usually stimulated by phosphatidylinositol 4,5-bisphosphate (PIP2) and activated by the ADP-ribosylation factor-1 (ARF-1). PLD2 is activated by agonist stimulation of both tyrosine kinase and G protein-coupled receptors and is also known to interact with EGFR and PIP5K1A. PLD2, localized to plasma membrane caveolae, is ubiquitously expressed in most tissues.
TRUSTED_SUSTAINABILITY

Specifikationer

Antigen PLD2
Användningsområden Immunohistochemistry (Paraffin), Western Blot
Klassificering Polyclonal
Koncentration 0.2 mg/mL
Konjugera Unconjugated
Formulering PBS with trehalose and no preservative
Gen Pld2
Genaccessionsnr. O14939
Gene Alias choline phosphatase 2; hPLD2; phosphatidylcholine-hydrolyzing phospholipase D2; phospholipase D gene 2; phospholipase D2; PLD 2; PLD1C; PLD2; Pldc; rPLD2
Gensymboler Pld2
Värd art Goat
Immunogen E. coli-derived recombinant human PLD2, Met1-His117.
Reningsmetod Antigen affinity chromatography
Kvantitet 100 μg
Regulatorisk status RUO
Primär eller sekundär Primary
Gen-ID (Entrez) 5338
Målarter Human
Innehåll och lagring Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Produkttyp Antibody
Form Lyophilized
Isotyp IgG
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Produkttitel
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