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PLZF Monoclonal Antibody (Mags.21F7), Alexa Fluor™ 488, eBioscience™, Invitrogen™

Mouse Monoclonal Antibody

1440.00 SEK - 3520.00 SEK

Specifications

Antigen PLZF
Clone Mags.21F7
Concentration 0.5 mg/mL
Applications Flow Cytometry
Classification Monoclonal
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Products 2
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Product Code Brand Quantity Price Quantity & Availability  
15570267
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Affymetrix eBioscience
53-9320-80
25 μg
1440.00 SEK
25µg
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Estimated Shipment: 09-04-2024
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15580267
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Affymetrix eBioscience
53-9320-82
100 μg
3520.00 SEK
100µg
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Description

Description

Description: This Mags.21F7 monoclonal antibody reacts with human and mouse promyelocytic leukemia zinc finger (PLZF), a member of the BTB-POZ family of transcription factors. Expression of this transcriptional repressor in immune cells differs between mice and humans. In mice, PLZF is highly expressed in immature CD1d-resricted NKT2 and NKT1 cells, and a subset of gamma delta (Vg1.1+Vd6.3+) T cells. Studies have also demonstrated expression of PLZF in non-invariant CD1d-restricted T cells, as well as non-CD1d-restricted innate T cells. In humans, PLZF is expressed in NK cells, gamma delta T cells, as well as CD4 and CD8+ T cells. PLZF is also expressed in MR1-specific mucosal-associated invariant T cells, as well as in MHC Class II-restricted T cells that develop via a thymocyte-thymocyte interaction in humans. PLZF exists as a homodimer or in complex with PLZP, and has been shown to be involved in the development of NKT cells, NK cell function, cellular quiescence, and growth suppression. Finally, PLZF has been shown to inhibit gene expression induced by retinoic acid receptor. Applications Reported: This Mags.21F7 antibody has been reported for use in intracellular staining followed by flow cytometric analysis. Applications Tested: This Mags.21F7 antibody has been tested by intracellular staining followed by flow cytometric analysis of mouse thymocytes. This can be used at less than or equal to 1 μg per test.

PLZF Monoclonal antibody specifically detects PLZF in Human, Mouse samples. It is validated for Flow Cytometry.
Specifications

Specifications

PLZF
0.5 mg/mL
Monoclonal
Liquid
RUO
PBS with 0.09% sodium azide; pH 7.2
AI467657; Green's luxoid; lu; luxoid; Lx; PLZF; Polydactyly-luxate syndrome; promyelocytic leukaemia zinc finger; promyelocytic leukemia zinc finger; Promyelocytic leukemia zinc finger protein; ZBTB16; Zfp145; zinc finger and BTB domain containing 16; zinc finger and BTB domain containing 16 protein; zinc finger and BTB domain-containing protein 16; Zinc finger protein 145; zinc finger protein 145 (Kruppel-like, expressed in promyelocytic leukemia); zinc finger protein PLZF; ZNF145
ZBTB16
Primary
4° C, store in dark, DO NOT FREEZE!
ZBTB16
Mags.21F7
Flow Cytometry
Alexa Fluor 488
Mouse
Human, Mouse
Q05516
235320, 7704
IgG1 κ
Affinity chromatography
Antibody
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