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Podoplanin, clone: NZ-1.3, eBioscience™

Rat Monoclonal Antibody

Brand:  Affymetrix eBioscience 14-9381-80

Additional Details : Weight : 0.01000kg

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Product Code. 15248167

  • 936.00 SEK / 25µg


EU Stock 4
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Description

Description

Description: Podoplanin is a 40-kDa type I transmembrane sialomucin-like glycoprotein involved in platelet aggregation and cancer metastasis. This protein is expressed on lymphatic endothelial cells and follicular dendritic cells, as well as on many human cancers, including squamous cell carcinoma, glioblastoma, seminoma, and mesothelioma. Podoplanin expression has been demonstrated to be regulated by the Fos protein of the Activating Protein-1 (AP-1) transcription factor complex. Much of its functionality arises via interaction with its endogenous receptor, C-type lectin-like receptor-2 (CLEC-2). This antibody has been reported to block the interaction between Podoplanin and CLEC-2.Applications Reported: This NZ-1.3 antibody has been reported for use in immunoprecipitation, immunoblotting (WB), and immunohistology staining of paraffin embedded tissue sections.Applications Tested: This NZ-1.3 antibody has been tested by immunoblot analysis of U87 cells. This can be used at 1-5μg per ml. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.Purity: Greater than 90%, as determined by SDS-PAGE.Aggregation: Less than 10%, as determined by HPLC.Filtration: 0.2μm post-manufacturing filtered.
Specifications

Specifications

Podoplanin
Monoclonal
0.5mg/mL
PBS with 0.09% sodium azide; pH 7.2
Q86YL7
CTA-520D8.1, AGGRUS, GP36, GP40, Gp38, HT1A-1, OTS8, PA2.26, T1A, T1A-2
Rat
Affinity chromatography
RUO
Antibody
Monoclonal
Human
Immunohistochemistry (Paraffin)þImmunoprecipitationþWestern Blot
NZ-1.3
Unconjugated
PDPN
Liquid
PDPN
IgG2a
25μg
Store at 2-8°C.
Primary
10630
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