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POFUT1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Brand: Proteintech 14929-1-AP-20UL
Additional Details : Weight : 0.00010kg
Description
POFUT1, an endoplasmic reticulum-residing member of the glycosyltransferase O-Fuc family, adds O-fucose through an O-glycosidic linkage to conserved serine or threonines in epidermal growth factor-like repeats of several cell surface and secreted proteins. Unlike its homolog POFUT2, POFUT1 can also catalyze the transfer of fucose to thrombospondin type 1 repeats. Many of the substrates of POFUT1 are involved in ligand-induced receptor signaling. One such protein is Notch; mouse ES cells lacking POFUT have normal levels of Notch receptors at the cell surface, but these receptors do not bind Notch ligands or exhibit Notch signaling.Specifications
| POFUT1 | |
| Polyclonal | |
| Unconjugated | |
| POFUT1 | |
| FUT12, KIAA0180, O Fuc T, O FucT 1, O FUT, Peptide O fucosyltransferase 1, POFUT1, protein O fucosyltransferase 1 | |
| Rabbit | |
| Antigen Affinity Chromatography | |
| RUO | |
| 140484, 23509, 311551 | |
| -20°C | |
| Liquid |
| Immunohistochemistry (Paraffin), Immunocytochemistry, Immunoprecipitation, Western Blot, Immunofluorescence | |
| 0.2 mg/mL | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
| Q6EV70, Q91ZW2, Q9H488 | |
| Pofut1 | |
| POFUT1 Fusion Protein Ag6710 | |
| 20 μL | |
| Primary | |
| Human, Rat, Mouse | |
| Antibody | |
| IgG |