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PROC Rabbit anti-Human, Mouse, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 25382-1-AP-20UL

Additional Details : Weight : 0.00010kg

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Product Code. 16823965

  • 1236.20 SEK / 20µL
Estimated Shipment: 02-12-2021

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Description

Description

Protein C is a vitamin K-dependent plasma glycoprotein that is cleaved to its activated form by the thrombin-thrombomodulin complex. Protein C in its activated form contains a serine protease domain and functions in degradation of the activated forms of coagulation factors V and VIII. Protein C is a vitamin K-dependent serine protease produced in the liver and made up of 2 polypeptide chains. The 62 kDa proenzyme is activated by thrombin bound to an endothelial surface receptor and the active enzyme cleaves factor Va and VIIIa and thus inhibits blood coagulation. The molecular weight of the active enzyme is 55kDa and the normal concentrations in human plasma is approximately 1-3 ng/ml because of the very fast turnover, the proenzyme concentration is approximately 3 μg/ml. Mutations in the Protein C gene have been associated with thrombophilia due to protein C deficiency, neonatal purpura fulmis, and recurrent venous thrombosis.
Specifications

Specifications

PROC
0.34 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
P04070, P33587
Anticoagulant protein C, Autoprothrombin IIA, Blood coagulation factor XIV, PC, PROC, PROC1, Vitamin K dependent protein C
Rabbit
IgG
20 μL
-20°C
Primary
19123, 5624
Western Blot, Immunohistochemistry (Paraffin)
Unconjugated
PROC
Liquid
Proc
PROC Fusion Protein Ag11328
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Mouse, Human
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