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Invitrogen™ PSAP Monoclonal Antibody (4D5F4)

Beskrivning
MA5-17159 targets PSAP in indirect ELISA, FACS, ICC, IHC, IF and WB applications and shows reactivity with Human samples. The MA5-17159 immunogen is purified recombinant fragment of human PSAP (amino acids: 325-524 ) expressed in E. Coli. MA5-17159 detects PSAP which has a predicted molecular weight of approximately 58.1kDa.
PSAP is a highly conserved glycoprotein which is a precursor for 4 cleavage products: saposins A, B, C, and D. Each domain of the precursor protein is approximately 80 amino acid residues long with nearly identical placement of cysteine residues and glycosylation sites. Saposins A-D localize primarily to the lysosomal compartment where they facilitate the catabolism of glycosphingolipids with short oligosaccharide groups. The precursor protein exists both as a secretory protein and as an integral membrane protein and has neurotrophic activities.
Specifikationer
Specifikationer
| Antigen | PSAP |
| Användningsområden | ELISA, Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry |
| Klassificering | Monoclonal |
| Klona | 4D5F4 |
| Koncentration | 1 mg/mL |
| Konjugera | Unconjugated |
| Formulering | PBS with 0.05% sodium azide |
| Gen | Psap |
| Genaccessionsnr. | P07602 |
| Gene Alias | A1 activator; AI037048; Cerebroside sulfate activator; Co-beta-glucosidase; Component C; CSAct; Dispersin; GLBA; Glucosylceramidase activator; Proactivator polypeptide; prosaposin; prosaposin (sulfated glycoprotein, sphingolipid hydrolase activator); Protein A; Protein C; Psap; SAP1; SAP-1; SAP-2; Saposin-A; Saposin-B; Saposin-B-Val; Saposin-C; Saposin-D; Sgp1; SGP-1; SGP1A; snoRNA MBII-198; Sphingolipid activator protein 1; Sphingolipid activator protein 2; sphingolipid activator protein-1; sulfated glycoprotein 1; Sulfatide/GM1 activator |
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Produkttitel
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