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PSMA/GCPII Mouse anti-Human, Rat, Clone: 3G4E12, Proteintech

Mouse Monoclonal Antibody

Brand:  Proteintech 66678-1-IG-20UL

Additional Details : Weight : 0.00010kg

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Product Code. 16828785

  • 1236.20 SEK / 20µL
Estimated Shipment: 08-12-2021

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Description

Description

PMSA (FOLH1) is a type II transmembrane glycoprotein belonging to the M28 peptidase family. Three functionally distinct proteins are encoded, including folylpoly-gamma-glutamate carboxypeptidase in the intestine, N-acetylated alpha-linked acidic dipeptidase 1 in the brain, and prostate-specific membrane antigen in the prostate. A mutation in the intestinal form may be associated with impaired intestinal absorption of dietary folates, resulting in low blood folate levels and consequent hyperhomocysteinemia. The form expressed in the brain may be involved in a number of pathological conditions associated with glutamate excitotoxicity. The prostate form is up-regulated in cancerous cells and is used as an effective diagnostic and prognostic indicator of prostate cancer. This gene likely arose from a duplication event of a nearby chromosomal region.
Specifications

Specifications

PSMA/GCPII
3G4E12
Unconjugated
FOLH1
Liquid
Folh1
PSMA/GCPII Fusion Protein Ag16594
Protein G
RUO
Antibody
Monoclonal
Human, Rat
Immunohistochemistry (Paraffin), Western Blot
1 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
P70627, Q04609
FGCP, Folate hydrolase 1, FOLH, FOLH1, GCP2, GCPII, Glutamate carboxypeptidase 2, Glutamate carboxypeptidase II, mGCP, NAALAD1, NAALAdase, NAALADase I, PSM, PSMA
Mouse
IgG1
20 μL
-20°C
Primary
2346, 85309
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