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Tocris Bioscience™ PX 12
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Product Code. 18015872
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18015872 10 mg
18044942 50 mg
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Product Code. 18015872 Supplier Tocris Bioscience™ Supplier No. 2954/10

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Description

Thioredoxin-1 inhibitor

Thioredoxin-1 (Trx-1) inhibitor; irreversibly inactivates Trx-1 as a substrate for reduction by thioredoxin reductase (TR); competitively inhibits the reduction of Trx-1 by TR (Ki = 30.8 μM). Attenuates expression of HIF-1α, VEGF and iNOS (IC50 values are 7.2, 10.4 and 18.1 μM respectively). Exhibits antitumor activity; directly inhibits tubulin in vitro and decreases tumor microvessel density in vivo.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 141400-58-0
Molekylformel C7H12N2S2

Specifications

Kemiskt namn eller material PX 12
Kvantitet 10 mg
Formel vikt 188.31
Renhet >99%
Molekylvikt (g/mol) 188.31
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