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STEMCELL Technologies Quercetin (Hydrate)

Produktkod. 17180292
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10 g
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17180292 10 g
17170292 5 g
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Produktkod. 17180292 Leverantör STEMCELL Technologies Leverantörsnummer 73934

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Beskrivning

mTOR, PI3K/AKT, NF-kB, and tyrosine kinase pathway inhibitor; Inhibits PI3K and SRC kinases

  • Quercetin inhibits phosphoinositide 3-kinase isoforms (beta: IC50 = 5.4 μM; gamma: IC50 = 2.4 μM; delta: IC50 = 3.0 μM) and SRC kinases but only shows slight inhibitory activity against serine/threonine kinases ERK1/2 and p38 alpha, as well as protein kinase C (Navarro-Nunez et al.)
  • Stimulates glycolytic metabolism and promotes reprogramming of somatic cells (Zhang et al.)
  • Enhances reprogramming of human primary somatic cells to induced pluripotent stem cells (Zhu et al.)
  • Induces hypoxia-inducible factor-1α (HIF-1α) and inhibits cell proliferation (Triantafyllou et al.)
  • Promotes apoptosis of glioblastoma cells when used together with temozolomide (Sang et al.)
  • Reduces tumorigenicity of pancreatic cancer cells (Fan et al.)

Specifikationer

CAS 849061-97-8
Kvantitet 10 g
Molekylformel C15H10O7 · XH2O
Renhet ≥95%
Produkttitel
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