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Tocris Bioscience™ PFI 4

Produktkod. 18758798
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Produktkod. Kvantitet
18758798 50 mg
18756228 10 mg
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Produktkod. 18758798 Leverantör Tocris Bioscience™ Leverantörsnummer 5576/50

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Beskrivning

Potent and selective BRPF1 bromodomain inhibitor

PFI 4 is a potent and selective BRPF1B bromodomain inhibitor (IC50 = 172 nM). Exhibits >100-fold selectivity for BRPF1 over a panel of other bromodomains including BRPF2 (BRD1), BRPF3 and BRD4. Disrupts BRPF1 binding to histone H3.3. Cell permeable. Inhibits osteoclastogenesis.
TRUSTED_SUSTAINABILITY

Specifikationer

Kemiskt namn eller material PFI 4
CAS 900305-37-5
Synonym N-[2,3-Dihydro-1,3-dimethyl-2-oxo-6-(1-pyrrolidinyl)-1H-benzimidazol-5-yl]-2-methoxybenzamide
Kvantitet 50 mg
Löslighet Soluble to 50mM in DMSO and to 10mM in ethanol
Molekylformel C21H24N4O3
Formel vikt 380.44
Fysisk form Solid
Produkttyp Bioactive Small Molecule
Renhet >99%

Research Use Only. Not For Human or Veterinary Use

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