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R406 free base, MedChemExpress

Produktkod. 16494398
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Produktkod. 16494398 Leverantör Medchem Express Leverantörsnummer HY11108

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MedChemExpress R406 free base is an orally available and competitive Syk/FLT3 inhibitor for ATP binding with a Ki of 30 nM, potently inhibits Syk kinase activity in vitro with an IC50 of 41 nM, measured at an ATP concentration corresponding to its Km value. R406 free base reduces immune complex-mediated inflammation. R406 free base also inhibits Lyn (IC50=63 nM) and Lck (IC50=37 nM).

R406 free base is an orally available and competitive Syk/FLT3 inhibitor for ATP binding with a Ki of 30 nM, potently inhibits Syk kinase activity in vitro with an IC50 of 41 nM, measured at an ATP concentration corresponding to its Km value. R406 free base reduces immune complex-mediated inflammation. R406 free base also inhibits Lyn (IC50=63 nM) and Lck (IC50=37 nM).

Specifikationer

Kemiskt namn eller material R406 free base
CAS 841290-80-0
Färg Light Yellow
Anteckningar om renhetsgrad Research
Molekylformel C22H23FN6O5
Kvantitet 10 mg
Löslighetsinformation DMSO : ≥ 10 mg/mL (21.26 mM)
LEDER COC1=CC(NC2=NC(NC3=NC(N4)=C(C=C3)OC(C)(C)C4=O)=C(C=N2)F)=CC(OC)=C1OC
Molekylvikt (g/mol) 470.45
Formel vikt 470.45
Procent renhet 98.15%
Kvalitet Research
Fysisk form Solid
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