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ABCB7 Rabbit anti-Human, Polyclonal Antibody, Abnova™
Beskrivning
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This gene encodes a half-transporter involved in the transport of heme from the mitochondria to the cytosol. With iron/sulfur cluster precursors as its substrates, this protein may play a role in metal homeostasis. Mutations in this gene have been implicated in X-linked sideroblastic anemia with ataxia. [provided by RefSeq
Specifikationer
Specifikationer
| Antigen | ABCB7 |
| Användningsområden | ELISA, Immunohistochemistry (PFA fixed), Western Blot |
| Klassificering | Polyclonal |
| Konjugera | Unconjugated |
| Beskrivning | Rabbit polyclonal antibody raised against synthetic peptide of ABCB7. |
| Utspädning | ELISA (1:1000) Western Blot (1:100-500) Immunohistochemistry (1:50-100) The optimal working dilution should be determined by the end user. |
| Formulering | In PBS (0.09% sodium azide) |
| Gen | ABCB7 |
| Genaccessionsnr. | NP_004290 |
| Gene Alias | ABC7/ASAT/Atm1p/EST140535 |
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For Research Use Only
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