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ALOX5 (phospho S523), Rabbit, Polyclonal Antibody, Abnova™

Produktkod. 16051768
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Kvantitet:
100 μL
Förpackningsstorlek:
100µL
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Produktkod. Kvantitet unitSize
16051768 100 μL 100µL
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Produktkod. 16051768 Leverantör Abnova Leverantörsnummer PAB9606.100uL

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Beskrivning

Rabbit polyclonal antibody raised against synthetic phosphopeptide of ALOX5.

This gene encodes a member of the lipoxygenase gene family and plays a dual role in the synthesis of leukotrienes from arachidonic acid. The encoded protein, which is expressed specifically in bone marrow-derived cells, catalyzes the conversion of arachidonic acid to 5(S)-hydroperoxy-6-trans-8,11,14-cis-eicosatetraenoic acid, and further to the allylic epoxide 5(S)-trans-7,9-trans-11,14-cis-eicosatetrenoic acid (leukotriene A4). Leukotrienes are important mediators of a number of inflammatory and allergic conditions. Mutations in the promoter region of this gene lead to a diminished response to antileukotriene drugs used in the treatment of asthma and may also be associated with atherosclerosis and several cancers. Alternatively spliced transcript variants have been observed, but their full-length nature has not been determined. [provided by RefSeq

Specifikationer

Antigen ALOX5
Användningsområden Western Blot
Klassificering Polyclonal
Konjugera Unconjugated
Beskrivning Rabbit polyclonal antibody raised against synthetic phosphopeptide of ALOX5.
Utspädning Western Blot (1:1000) The optimal working dilution should be determined by the end user.
Formulering In 10mM HEPES, 150mM NaCl, pH 7.5 (50% glycerol, 10% BSA)
Gen ALOX5
Genaccessionsnr. P09917
Gene Alias 5-LO/5-LOX/5LPG/LOG5/MGC163204
Gensymboler ALOX5
Värd art Rabbit
Immunogen Synthetic phosphopeptide corresponding to residues surrounding S523 of human ALOX5.
Reningsmetod Affinity purification
Kvantitet 100 μL
Regulatorisk status RUO
Primär eller sekundär Primary
Gen-ID (Entrez) 240
Målarter Human, Primate, Rat
Innehåll och lagring Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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For Research Use Only

Produkttitel
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