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BAD (phospho S134), Rabbit anti-Human, Polyclonal Antibody, Abnova™
Beskrivning
The protein encoded by this gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform. [provided by RefSeq
Specifikationer
Specifikationer
| Antigen | BAD |
| Användningsområden | ELISA, Immunohistochemistry (Paraffin), Western Blot |
| Klassificering | Polyclonal |
| Konjugera | Unconjugated |
| Beskrivning | Rabbit polyclonal antibody raised against synthetic phosphopeptide of BAD. |
| Utspädning | Western Blot (1:1000) Immunohistochemistry (1:50-100) The optimal working dilution should be determined by the end user. |
| Formulering | In PBS (0.09% sodium azide) |
| Gen | BAD |
| Genaccessionsnr. | NP_116784;Q92934 |
| Gene Alias | BBC2/BCL2L8 |
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For Research Use Only
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