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CBL (phospho Y700), Rabbit anti-Human, Polyclonal Antibody, Abnova™
Beskrivning
The cbl oncogene was first identified as part of a transforming retrovirus which induces mouse pre-B and pro-B cell lymphomas. As an adaptor protein for receptor protein-tyrosine kinases, it positively regulates receptor protein-tyrosine kinase ubiquitination in a manner dependent upon its variant SH2 and RING finger domains. Ubiquitination of receptor protein-tyrosine kinases terminates signaling by marking active receptors for degradation. [provided by RefSeq
Specifikationer
Specifikationer
| Antigen | CBL |
| Användningsområden | Immunofluorescence, Immunohistochemistry (PFA fixed) |
| Klassificering | Polyclonal |
| Koncentration | 1 mg/mL |
| Konjugera | Unconjugated |
| Beskrivning | Rabbit polyclonal antibody raised against synthetic phosphopeptide of CBL. |
| Utspädning | Immunohistochemistry (1:50-1:100) Immunofluorescence (1:100-1:200) The optimal working dilution should be determined by the end user. |
| Formulering | In PBS (without mg2+ and Ca2+), 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide) |
| Gen | CBL |
| Genaccessionsnr. | P22681 |
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For Research Use Only
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