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DOK1 (phospho Y362), Rabbit anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova™
Beskrivning
Docking protein 1 is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210(bcr/abl), a chimeric protein whose presence is associated with CML. Docking protein 1 contains a putative pleckstrin homology domain at the amino terminus and ten PXXP SH3 recognition motifs. Docking protein 2 binds p120 (RasGAP) from CML cells. It has been postulated to play a role in mitogenic signaling. [provided by RefSeq
Specifikationer
Specifikationer
| Antigen | DOK1 |
| Användningsområden | ELISA, Western Blot |
| Klassificering | Polyclonal |
| Konjugera | Unconjugated |
| Beskrivning | Rabbit polyclonal antibody raised against synthetic phosphopeptide of DOK1. |
| Utspädning | ELISA (1:2000) Western Blot (1:500) The optimal working dilution should be determined by the end user. |
| Formulering | In PBS (50% glycerol, 1mg/mL BSA, 0.05% sodium azide) |
| Gen | DOK1 |
| Gene Alias | MGC117395/MGC138860/P62DOK |
| Gensymboler | DOK1 |
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For Research Use Only
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