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HDAC1 (phospho S421/S423), Rabbit anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova™
Description
Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis. [provided by RefSeq
Specifications
Specifications
| Antigen | HDAC1 |
| Användningsområden | ELISA, Immunohistochemistry (PFA fixed), Western Blot |
| Klassificering | Polyclonal |
| Konjugera | Unconjugated |
| Beskrivning | Rabbit polyclonal antibody raised against synthetic phosphopeptide of HDAC1. |
| Utspädning | Western Blot (1:500-1:1000) Immunohistochemistry (1:50-1:100) ELISA (1:4000) The optimal working dilution should be determined by the end user. |
| Formulering | In 20mM PBS, 0.15M NaCl, pH 7.2 (0.01% sodium azide) |
| Gen | HDAC1 |
| Gene Alias | DKFZp686H12203/GON-10/HD1/RPD3/RPD3L1 |
| Gensymboler | HDAC1 |
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For Research Use Only
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