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MAP3K7IP3 Rabbit anti-Human, Polyclonal Antibody, Abnova™
Beskrivning
The product of this gene functions in the NF-kappaB signal transduction pathway. The encoded protein, and the similar and functionally redundant protein MAP3K7IP2/TAB2, forms a ternary complex with the protein kinase MAP3K7/TAK1 and either TRAF2 or TRAF6 in response to stimulation with the pro-inflammatory cytokines TNF or IL-1. Subsequent MAP3K7/TAK1 kinase activity triggers a signaling cascade leading to activation of the NF-kappaB transcription factor. The human genome contains a related pseudogene. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq
Specifikationer
Specifikationer
| Antigen | MAP3K7IP3 |
| Användningsområden | ELISA, Immunohistochemistry |
| Klassificering | Polyclonal |
| Koncentration | 1 mg/mL |
| Konjugera | Unconjugated |
| Beskrivning | Rabbit polyclonal antibody raised against synthetic peptide of MAP3K7IP3. |
| Utspädning | Immunohistochemistry (5 ug/mL) The optimal working dilution should be determined by the end user. |
| Formulering | In PBS (0.02% sodium azide) |
| Gen | MAP3K7IP3 |
| Gene Alias | MGC45404/NAP1/TAB3 |
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For Research Use Only
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