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PSMD10 Rabbit anti-Bovine, Human, Mouse, Pig, Rat, Zebra fish, Polyclonal Antibody, Abnova™
Beskrivning
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 nonidentical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a nonlysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. Two transcripts encoding different isoforms have been described. Pseudogenes have been identified on chromosomes 3 and 20. [provided by RefSeq
Specifikationer
Specifikationer
| Antigen | PSMD10 |
| Användningsområden | Western Blot |
| Klassificering | Polyclonal |
| Konjugera | Unconjugated |
| Beskrivning | Rabbit polyclonal antibody raised against synthetic peptide of PSMD10. |
| Utspädning | Western Blot (2 ug/mL) The optimal working dilution should be determined by the end user. |
| Formulering | In Tris-glycine, 150mM NaCl (0.05% sodium azide) |
| Gen | PSMD10 |
| Gene Alias | dJ889N15.2/p28 |
| Gensymboler | PSMD10 |
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For Research Use Only
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