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RAF1 (phospho T269), Rabbit anti-Human, Polyclonal Antibody, Abnova™

Produktkod. 16058856
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Kvantitet:
400 μL
Förpackningsstorlek:
400µL
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16058856 400 μL 400µL
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Produktkod. 16058856 Leverantör Abnova Leverantörsnummer PAB0594.400uL

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Beskrivning

Rabbit polyclonal antibody raised against synthetic phosphopeptide of RAF1.

This gene is the cellular homolog of viral raf gene (v-raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine/threonine specific protein kinases, ERK1 and ERK2. Activated ERKs are pleiotropic effectors of cell physiology and play an important role in the control of gene expression involved in the cell division cycle, apoptosis, cell differentiation and cell migration. Mutations in this gene are associated with Noonan syndrome 5 and LEOPARD syndrome 2. [provided by RefSeq

Specifikationer

Antigen RAF1
Användningsområden Dot Blot, ELISA
Klassificering Polyclonal
Konjugera Unconjugated
Beskrivning Rabbit polyclonal antibody raised against synthetic phosphopeptide of RAF1.
Utspädning Dot Blot (1:100-500) The optimal working dilution should be determined by the end user.
Formulering In PBS (0.09% sodium azide)
Gen RAF1
Gene Alias CRAF/NS5/Raf-1/c-Raf
Gensymboler RAF1
Värd art Rabbit
Immunogen Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding T269 of human RAF1.
Reningsmetod Protein A purification
Kvantitet 400 μL
Regulatorisk status RUO
Primär eller sekundär Primary
Gen-ID (Entrez) 5894
Målarter Human
Innehåll och lagring Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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For Research Use Only

Produkttitel
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