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SMC1A (phospho S957), Rabbit anti-Human, Mouse, Polyclonal Antibody, Abnova™

Produktkod. 16095597
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Kvantitet:
100 μg
Unit Size:
100µg
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16095597 100 μg 100µg
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Product Code. 16095597 Supplier Abnova Supplier No. PAB25427.100ug

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Description

Rabbit polyclonal antibody raised against synthetic phosphopeptide of SMC1A.

Proper cohesion of sister chromatids is a prerequisite for the correct segregation of chromosomes during cell division. The cohesin multiprotein complex is required for sister chromatid cohesion. This complex is composed partly of two structural maintenance of chromosomes (SMC) proteins, SMC3 and either SMC1L2 or the protein encoded by this gene. Most of the cohesin complexes dissociate from the chromosomes before mitosis, although those complexes at the kinetochore remain. Therefore, the encoded protein is thought to be an important part of functional kinetochores. In addition, this protein interacts with BRCA1 and is phosphorylated by ATM, indicating a potential role for this protein in DNA repair. This gene, which belongs to the SMC gene family, is located in an area of the X-chromosome that escapes X inactivation. [provided by RefSeq

Sequence: G-S-Sp-Q-G

Specifications

Antigen SMC1A
Användningsområden Immunohistochemistry (PFA fixed), Western Blot
Klassificering Polyclonal
Konjugera Unconjugated
Beskrivning Rabbit polyclonal antibody raised against synthetic phosphopeptide of SMC1A.
Utspädning Western Blot (1:500-1:1000) Immunohistochemistry (1:50-100) The optimal working dilution should be determined by the end user.
Formulering In PBS (without Mg2+ and Ca2+), 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
Gen SMC1A
Gene Alias CDLS2/DKFZp686L19178/DXS423E/KIAA0178/MGC138332/SB1.8/SMC1/SMC1L1/SMC1alpha/SMCB
Gensymboler SMC1A
Värd art Rabbit
Immunogen Synthetic phosphopeptide corresponding to residues surrounding S957 of human SMC1A.
Reningsmetod Affinity purification
Kvantitet 100 μg
Regulatorisk status RUO
Primär eller sekundär Primary
Gen-ID (Entrez) 8243
Målarter Human, Mouse
Innehåll och lagring Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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For Research Use Only

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