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VAV1 (phospho Y174), Rabbit anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova™

Produktkod. 16075597
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Kvantitet:
100 μg
Förpackningsstorlek:
100µg
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Produktkod. 16075597 Leverantör Abnova Leverantörsnummer PAB25422.100ug

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Rabbit polyclonal antibody raised against synthetic phosphopeptide of VAV1.

The protein encoded by this proto-oncogene is a member of the Dbl family of guanine nucleotide exchange factors (GEF) for the Rho family of GTP binding proteins. The protein is important in hematopoiesis, playing a role in T-cell and B-cell development and activation. This particular GEF has been identified as the specific binding partner of Nef proteins from HIV-1. Coexpression and binding of these partners initiates profound morphological changes, cytoskeletal rearrangements and the JNK/SAPK signaling cascade, leading to increased levels of viral transcription and replication. [provided by RefSeq

Sequence: E-I-Yp-E-D

Specifikationer

Antigen VAV1
Användningsområden Western Blot
Klassificering Polyclonal
Konjugera Unconjugated
Beskrivning Rabbit polyclonal antibody raised against synthetic phosphopeptide of VAV1.
Utspädning Western Blot (1:500-1:1000) The optimal working dilution should be determined by the end user.
Formulering In PBS (without Mg2+ and Ca2+), 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
Gen VAV1
Gene Alias VAV
Gensymboler VAV1
Värd art Rabbit
Immunogen Synthetic phosphopeptide corresponding to residues surrounding Y174 of human VAV1.
Reningsmetod Affinity purification
Kvantitet 100 μg
Regulatorisk status RUO
Primär eller sekundär Primary
Gen-ID (Entrez) 7409
Målarter Human, Mouse, Rat
Innehåll och lagring Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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For Research Use Only

Produkttitel
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