RASSF1A Mouse anti-Human, Clone: eB114-10H1, eBioscience™
Mouse Monoclonal Antibody
Brand: Affymetrix eBioscience 14-6888-82
Additional Details : Weight : 0.01000kg
DescriptionThis gene encodes a protein similar to the RAS effector proteins. Loss or altered expression of this gene has been associated with the pathogenesis of a variety of cancers, which suggests the tumor suppressor function of this gene. The inactivation of this gene was found to be correlated with the hypermethylation of its CpG-island promoter region. The encoded protein was found to interact with DNA repair protein XPA. The protein was also shown to inhibit the accumulation of cyclin D1, and thus induce cell cycle arrest. Seven alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
|PBS with 0.09% sodium azide; pH 7.2|
|123F2, NORE2A, RASSF1A, RDA32, REH3P21, WUGSC:H_LUCA12.5, cardiac-specific ras association domain family 1 protein, pancreas-specific ras association domain family 1 protein, ras association domain-containing protein 1, tumor suppressor protein RDA32|
|Immunoprecipitation, Western Blot|
For Research Use Only.