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RASSF1A Mouse anti-Human, Clone: eB114-10H1, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 14-6888-82

Additional Details : Weight : 0.01000kg

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Product Code. 15237957

  • 2565.00 SEK / 100µg


Estimated Shipment date
from Supplier 03-06-2019
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Description

Description

This gene encodes a protein similar to the RAS effector proteins. Loss or altered expression of this gene has been associated with the pathogenesis of a variety of cancers, which suggests the tumor suppressor function of this gene. The inactivation of this gene was found to be correlated with the hypermethylation of its CpG-island promoter region. The encoded protein was found to interact with DNA repair protein XPA. The protein was also shown to inhibit the accumulation of cyclin D1, and thus induce cell cycle arrest. Seven alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
Specifications

Specifications

RASSF1A
Monoclonal
0.5 mg/mL
PBS with 0.09% sodium azide; pH 7.2
Q9NS23
123F2, NORE2A, RASSF1A, RDA32, REH3P21, WUGSC:H_LUCA12.5, cardiac-specific ras association domain family 1 protein, pancreas-specific ras association domain family 1 protein, ras association domain-containing protein 1, tumor suppressor protein RDA32
Mouse
Affinity chromatography
RUO
Antibody
Monoclonal
Human
Immunoprecipitation, Western Blot
eB114-10H1
Unconjugated
RASSF1
Liquid
RASSF1
IgG1, kappa
100 μg
4° C
Primary
11186
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