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RCAN2 Rabbit anti-Human, Mouse, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

1355.00 SEK - 3665.00 SEK

Specifications

Antigen RCAN2
Concentration 0.13 mg/mL
Applications Immunoprecipitation, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Conjugate Unconjugated
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
16840854
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Proteintech
12900-1-AP-150UL
150 μL
3665.00 SEK
150µL
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Estimated Shipment: 07-12-2022
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16850854
View Documents Promotion Details
Proteintech
12900-1-AP-20UL
20 μL
1355.00 SEK
20µL
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Estimated Shipment: 07-12-2022
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Description

Description

Regulator of calcineurin 2 (RCAN2), also known as ZAKI4 and DSCR1L1, is expressed as two isoforms differing at their N-terminus. The longer of the two (isoform 1) is expressed exclusively in the brain, while isoform 2 is ubiquitously expressed, with highest expression in brain, heart, and muscle. Both isoforms bind to the catalytic subunit of calcineurin, a Ca++-dependent protein phosphatase involved in several neuronal functions, though their C-terminal region and inhibit calcineurin′s activity. Unlike isoform 1 of RCAN2, the expression of the second isoform is not induced by the thyroid hormone T3. RCAN2 is a member of a family of three endogenous calcineurin regulators that are located near the minimal supernumerary fragment of chromosome 21 in individuals with Down syndrome, suggesting that they play a role in this syndrome. Multiple isoforms of RCAN2 are known to exist.
Specifications

Specifications

RCAN2
Immunoprecipitation, Immunohistochemistry (Paraffin), Western Blot
Unconjugated
Rabbit
Human, Mouse
Q14206, Q9JHG2
10231, 53901
RCAN2 Fusion Protein Ag3597
Primary
-20°C
RCAN2
0.13 mg/mL
Polyclonal
Liquid
RUO
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Calcipressin 2, CSP2, DSCR1L1, hRCN2, MCIP2, RCAN2, regulator of calcineurin 2, ZAKI 4, ZAKI4
Rcan2
IgG
Antigen Affinity Chromatography
Antibody
SDS
Product Certifications