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Invitrogen™ REA Polyclonal Antibody

Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA521417
Beskrivning
Recommended positive controls: H1299, HeLa, mouse brain. Predicted reactivity: Mouse (100%), Rat (100%), Xenopus laevis (87%), Pig (98%), Chicken (95%), Rhesus Monkey (100%), Bovine (99%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
PHB2 acts as a mediator of transcriptional repression by nuclear hormone receptors via recruitment of histone deacetylases. This protein functions as an estrogen receptor (ER)-selective coregulator that potentiates the inhibitory activities of antiestrogens and represses the activity of estrogens. It competes with NCOA1 for modulation of ER transcriptional activity. It is probably involved in regulating mitochondrial respiration activity and in aging.
Specifikationer
| REA | |
| Polyclonal | |
| Unconjugated | |
| PHB2 | |
| AU044498; BAP; Bap37; Bap-37; Bcap27; BCAP37; B-cell associated protein; B-cell receptor associated protein 37; B-cell receptor-associated protein 37; B-cell receptor-associated protein BAP37; D-prohibitin; hBAP; MGC117268; p22; phb2; phb2 {ECO:0000250; PNAS-141; prohibitin 2; prohibitin-2; Rea; Repressor of estrogen receptor activity; UniProtKB:Q99623} | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 11331, 114766, 12034 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry | |
| 0.66 mg/mL | |
| 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7 | |
| O35129, Q5XIH7, Q99623 | |
| PHB2 | |
| Recombinant protein encompassing a sequence within the center region of human Prohibitin 2. The exact sequence is proprietary. | |
| 100 μL | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |
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