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R&D Systems™ Recombinant Mouse IFN-alpha 2/IFNA2 Protein

Produktkod. 18776896
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Kvantitet:
10 μg
50 μg
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Produktkod. Kvantitet
18776896 10 μg
18736276 50 μg
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Produktkod. 18776896 Leverantör R&D Systems™ Leverantörsnummer 10149IF010
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Beräknad leverans: 15-10-2026
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Beskrivning

Interferon-alpha 2 (IFN alpha -2) is one of 14 subtypes within the IFN-alpha class of Type I Interferons

  • IFN-alpha class members signal through a common cell surface receptor complex composed of IFN-alpha R2 and IFN-alpha R1 subunits
  • The mature extracellular domain (ECD) of mouse IFN alpha -2 shares 60% and 83% aa sequence identity with human and rat, respectively
  • Murine IFN-alpha 2 can eliminate cardiac viral load and protect cardiomyocytes from injury in animals infected with coxsackievirus B3 (CVB3)
  • IFN alpha -2 derived mutants with reduced IFNR2 binding inhibited HIV replication and mutants with more IFNAR1 binding potentiated antiviral activity
TRUSTED_SUSTAINABILITY

Specifikationer

Tillträdesnummer P01573
För användning med (applikation) Bioactivity
Gen-ID (Entrez) 3440
Molekylvikt (g/mol) 19.3 kDa
Reningsmetod >95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie™ Blue Staining
Kvantitet 10 μg
Källa Human embryonic kidney cell, HEK293-derived mouse IFN-alpha 2/IFNA2 protein Cys24-Glu190
Förvaringskrav Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -70°C as supplied. 1 month, 2 to 8°C under sterile conditions after opening. 3 months, -20 to -70°C under sterile conditions after opening.
Endotoxinkoncentration <0.10 EU per 1 μg of the protein by the LAL method
Konjugera Unconjugated
Rekonstitution Reconstitute at 100 μg/mL in PBS
Buffert Lyophilized from a 0.2 μm filtered solution in PBS
Produktlinje R&D Systems
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