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R&D Systems™ Recombinant Mouse VSIG4 Fc Chimera Protein

Produktkod. 18166550
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Kvantitet:
50 μg
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Produktkod. 18166550

Brand: R&D Systems™ 4674VS050

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4464.00 SEK valid until 2025-12-16
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Beskrivning

Extensive quality control produces industry leading bioactivity and lot-to-lot consistency that instills confidence in results and ensures reproducibility.

Measured by its ability to inhibit anti-CD3-induced proliferation of splenic T lymphocytes. Vogt, L. et al. (2006) J. Clin. Invest. 116:2817. The presence of immobilized Recombinant Mouse VSIG4 Fc Chimera inhibited the anti-CD3 response by =50%. The ED50 for this effect is 1.25-5 μg/mL.
TRUSTED_SUSTAINABILITY

Specifications

Tillträdesnummer NP_808457
För användning med (applikation) Bioactivity
Formulering Lyophilized from a 0.2 μm filtered solution in PBS.
Gen-ID (Entrez) 11326
Molekylvikt (g/mol) M.W. (Observed): 60-65 kDa, reducing conditions; M.W. (theoretical): 46 kDa (monomer)
Namn VSIG4 Fc Chimera
Kvantitet 50 μg
Källa Mouse myeloma cell line, NS0-derived mouse VSIG4 protein Mouse VSIG4 (His20-Pro187) (N-terminus) Accession # NP_808457 IEGRMDP Mouse IgG2A (Glu98-Lys330) (C-terminus)
Förvaringskrav Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20°C to -70°C as supplied. 1 month, 2°C to 8°C under sterile conditions after reconstitution. 3 months, -20°C to -70°C under sterile conditions after reconstitution.
Strukturell form Disulfide-linked homodimer
Endotoxinkoncentration <1.0 EU / 1 μg of the protein by the LAL method.
Gensymbol Vsig4
Konjugera Unconjugated
Rekombinant Recombinant
Rekonstitution Reconstitute at 200 μg/mL in sterile PBS.
Renhet eller kvalitetsklass >90%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie™ Blue Staining.
Protein VSIG4
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