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Rifamycin SV Sodium Salt, MP Biomedicals™
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Quantity:
250 mg
Description
Rifamycin SV inhibits selective (E. coli, B. subtilis) bacterial DNA-dependent RNA polymerase by binding to the polymerase β-subunit, a mechanism similar to rifabutin. It acts as a selective cytochrome P450 3A4 inducer. It has limited oral absorption. It is active against Gram-positive bacteria and is moderately active against Gram-negative organisms.
- Used to study potential genes, such as rif15 and rif16, which may be involved in the conversion of rifamycin SV into rifamycin B
- Potential treatment for traveler’s diarrhea (TD), Clostridium difficile-associated disease (CDAD) and rheumatoid knee synovitis
- It is used in electron spin resonance studies
Specifications
| CAS | 14897-39-3 |
| Molecular Formula | C37H47NNaO12 |
| MDL Number | MFCD09752825 |
| Quantity | 250 mg |
| Synonym | rifamycin sodium salt, rifamycin sodium usan, rifamycin sv sodium salt, rifocina tn, otofa tn |
| Solubility Information | Ethanol: soluble (50mg/mL) |
| InChI Key | YVOFSHPIJOYKSH-DITFEXNXSA-N |
| SMILES | [Na+].CO[C@H]1\C=C/O[C@@]2(C)OC3=C(C)C(O)=C4C(O)=C(NC(=O)\C(C)=C/C=C\[C@H](C)[C@H](O)[C@@H](C)[C@@H](O)[C@@H](C)[C@H](OC(C)=O)[C@@H]1C)C=C(O)C4=C3C2=O |
| IUPAC Name | sodium (7S,9Z,11S,12R,13S,14R,15R,16R,17S,18S,19Z,21Z)-2,15,17,27,29-pentahydroxy-11-methoxy-3,7,12,14,16,18,22-heptamethyl-6,23-dioxo-8,30-dioxa-24-azatetracyclo[23.3.1.1⁴,⁷.0⁵,²⁸]triaconta-1,3,5(28),9,19,21,25(29),26-octaen-13-yl acetate |
| Molecular Weight (g/mol) | 720.77 |
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