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RLN3 Rabbit anti-Human, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 26075-1-AP-20UL

Additional Details : Weight : 0.00010kg

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Product Code. 16824605

  • 1236.20 SEK / 20µL
Estimated Shipment: 07-12-2021

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Description

Description

Relaxin 3 is part of the Relaxin-like peptide family that plays an important neuropeptide signaling role. Relaxin 3 is a ligand for two structurally related G protein-coupled receptors, human Relaxin receptor 3 and Relaxin receptor 4. The greatest levels of Relaxin 3 expression occur in the brain, specifically in the pons/medulla, with highest levels in the pars ventromedialis of the dorsal tegmental nucleus and with lower levels in the hippocampus and olfactory regions. Significant expression is also observed in the spleen, thymus, lung and ovary. Relaxin 3 inhibits Forskolin-stimulated cAMP accumulation in a dose-dependent manner in cells that express Relaxin receptor 3. Acute and repeated administration of Relaxin 3 causes a decrease in levels of the plasma thyroid stimulating hormone, suggesting that Relaxin 3 may play a role in long-term control of food intake.
Specifications

Specifications

RLN3
0.3 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Q8WXF3
H3, insl7, Insulin like peptide 7, Insulin like peptide INSL7, Prorelaxin H3, relaxin 3, RLN3, RXN3, ZINS4
Rabbit
IgG
20 μL
-20°C
Primary
117579
Immunohistochemistry (Paraffin)
Unconjugated
RLN3
Liquid
RLN3
RLN3 Fusion Protein Ag23382
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human
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