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ROR gamma (t), clone: B2D, eBioscience™

Rat Monoclonal Antibody

Brand:  Affymetrix eBioscience 14-6981-82

Additional Details : Weight : 0.01000kg

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Product Code. 15257957

  • 2970.00 SEK / 100µg


Estimated Shipment date
from Supplier 28-08-2018
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Description

Description

Description: The B2D monoclonal antibody reacts with the mouse RORgamma(t) protein. RORgamma is a member of the retinoic acid-related orphan receptor (ROR) family, which also includes RORalpha and RORbeta. ROR family proteins are ligand-dependent transcription factors that play roles in multiple physiological processes. RORgamma is expressed in several tissues including liver, lung, muscle, heart and kidney. Furthermore, it was discovered that alternative transcription results in the expression of an isoform, RORgammat, which is expressed exclusively in cells of the lymphoid compartment, namely CD4+CD8+ double-positive thymoyctes, Th17 cells of the periphery and lymphoid tissue inducer (Lti) cells of lymphoid organs. The RORgammat isoform differs from RORgamma by three unique amino acids at the amino terminus. Therefore, the B2D antibody will react with both the RORgamma and RORgammat isoforms.Applications Reported: This B2D antibody has been reported for use in immunoblotting (WB).Applications Tested: This B2D antibody has been tested by western blot analysis of mouse thymus nuclear lysates. This B2D antibody can be used at a starting concentration of 2 ug/ml, however the optimal concentration should be determined for individual experimental conditions.Purity: Greater than 90%, as determined by SDS-PAGE.Aggregation: Less than 10%, as determined by HPLC.Filtration: 0.2μm post-manufacturing filtered.
Specifications

Specifications

ROR gamma (t)
Monoclonal
0.5mg/mL
PBS with 0.09% sodium azide; pH 7.2
P51450
MGC129539, NR1F3, RORG, RZR-GAMMA, RZRG, TOR
Rat
Affinity chromatography
RUO
Antibody
Monoclonal
Murine
Western Blot
B2D
Unconjugated
Rorc
Liquid
Rorc
IgG1, kappa, kappa
100μg
4° C
Primary
19885
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