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RORA Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 10616-1-AP-20UL

Additional Details : Weight : 0.00010kg

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Product Code. 16877103

  • 1656.73 SEK / 20µL
Estimated Shipment: 03-04-2024
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Description

Description

RORA is a receptor for retinoic acid belonging to the NR1 subfamily of nuclear hormone receptors with a nuclear receptor DNA binding domain. RORA binds either as a monomer or as a homodimer to the retinoic acid response element and thus regulates gene expression and also controls cell function. Though the exact function of RORA is yet unknown, it interacts with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation, NM23-1, the product of a tumor metastasis suppressor candidate gene, CDK7, NCOA3 and NCOA6 coactivators. It is found to express in mesenchymal stem cells derived from bone marrow and are known to act by direct modulation of a bone matrix component. It is widely expressed in most of the tissues. Chromosomal aberrations involving RORA may be a cause of acute promyelocytic leukemia (APL).
Specifications

Specifications

RORA
Polyclonal
Unconjugated
RORA
NR1F1, Nuclear receptor ROR alpha, Nuclear receptor RZR alpha, RAR related orphan receptor A, ROR1, ROR2, ROR3, RORA, RZR ALPHA, RZRA
Rabbit
Antigen Affinity Chromatography
RUO
19883, 300807, 6095
-20°C
Liquid
Western Blot
0.25 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
P35398, P51448
RORA
RORA Fusion Protein Ag0944
20 μL
Primary
Rat, Mouse, Human
Antibody
IgG
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